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Cellutron products referenced in journal publications

 

                                                                                                                                              

 

Sci Adv. 2023 Nov 24;9(47):eadj4846. doi: 10.1126/sciadv.adj4846. Epub 2023 Nov 24
Mapping cardiac remodeling in chronic kidney disease

 

Front Cardiovasc Med. 2023 May 22:10:1096884. doi: 10.3389/fcvm.2023.1096884. eCollection 2023.
A fully-automated low-cost cardiac monolayer optical mapping robot

 

J Clin Invest. 2022 Nov 15;132(22):e158897. doi: 10.1172/JCI158897.
Loss of function of the nuclear envelope protein LEMD2 causes DNA damage–dependent

cardiomyopathy

 

Sci Rep. 2022 Jul 6;12(1):11416. doi: 10.1038/s41598-022-15559-y
p63 silencing induces epigenetic modulation to enhance human cardiac fibroblast to

cardiomyocyte-like differentiation

 

Cells 2022 Jul 4;11(13):2111. doi: 10.3390/cells11132111

Activation of Autophagic Flux Maintains Mitochondrial Homeostasis during Cardiac Ischemia/Reperfusion Injury

 

Front Bioeng Biotechnol 2022 May 17;10:920730. doi: 10.3389/fbioe.2022.920730. eCollection 2022

functional and smart biomaterials: development and application in regenerative medicine

 

Dev Cell2020 Apr 6;53(1):42-59.e11. doi: 10.1016/j.devcel.2020.01.030. Epub 2020 Feb 27

Lamin B2 Levels Regulate Polyploidization of Cardiomyocyte Nuclei and Myocardial Regeneration

 

Nature Commun. 2020 Apr 14;11(1):1771. doi: 10.1038/s41467-020-15640-y.

Chronic activation of hexosamine biosynthesis in the heart triggers pathological cardiac remodeling

 

PLoS One 2020 Aug 24;15(8):e0237591. doi: 10.1371/journal.pone.0237591. eCollection 2020.

The auxiliary subunit KCNE1 regulates KCNQ1 channel response to sustained calcium-dependent PKC activation

 

Am J Physiol Cell Physiol. 2020 Jan 1;318(1):C163-C173. doi: 10.1152/ajpcell.00107.2019. Epub 2019 Nov 20.

Real-time visualization of titin dynamics reveals extensive reversible photobleaching in human induced pluripotent stem cell-derived cardiomyocytes

 

J Am Heart Assoc. 2020 Jun 16;9(12):e015686. doi: 10.1161/JAHA.119.015686. Epub 2020 Jun 5

Enhanced Generation of Induced Cardiomyocytes Using a Small‐Molecule Cocktail to Overcome Barriers to Cardiac Cellular Reprogramming


J Am Heart Assoc. 2019 Aug 6;8(15):e011012. doi: 10.1161/JAHA.118.011012. Epub 2019 Jul 17.
Deletion of the Cardiomyocyte Glucocorticoid Receptor Leads to Sexually Dimorphic Changes in Cardiac Gene Expression and Progression to Heart Failure

 

Biomed Pharmacother 2019 Oct;118:109391. doi: 10.1016/j.biopha.2019.109391. Epub 2019 Aug 28

Effects of hypoxia on cardiomyocyte proliferation and association with stage of development

 

Nat Commun. 2019 Jan 18;10(1):329. doi: 10.1038/s41467-018-08276-6.
A selective inhibitor of mitofusin 1-ßIIPKC association improves heart failure outcome in rats

 

J Cell Biochem. 2018 Apr;119(4):3363-3372. doi: 10.1002/jcb.26501. Epub 2018 Jan 15.
Acute hypoxic preconditioning prevents palmitic acid-induced cardiomyocyte apoptosis via switching metabolic GLUT4-glucose pathway back to CD36-fatty acid dependent

 

EMBO Mol Med. 2018 Mar;10(3). pii: e8237. doi: 10.15252/emmm.201708237.
CRTH2 promotes endoplasmic reticulum stress-induced cardiomyocyte apoptosis through m-calpain

 

J Vis Exp. 2018 Jun 3;(136). doi: 10.3791/57687.
Suppression of Pro-fibrotic Signaling Potentiates Factor-mediated Reprogramming of Mouse Embryonic Fibroblasts into Induced Cardiomyocytes

 

Nat Commun. 2018 Feb 16;9(1):700. doi: 10.1038/s41467-018-03019-z.
Loss of microRNA-128 promotes cardiomyocyte proliferation and heart regeneration

 

Circ Res. 2018 Jan 5;122(1):74-87. doi: 10.1161/CIRCRESAHA.117.311349. Epub 2017 Oct 11.
Mitochondrial Cardiomyopathy Caused by Elevated Reactive Oxygen Species and Impaired Cardiomyocyte Proliferation

 

Genes Dev. 2017 Sep 1;31(17):1770-1783. doi: 10.1101/gad.305482.117.
ZNF281 enhances cardiac reprogramming by modulating cardiac and inflammatory gene expression


Data Brief. 2017 Nov 20;16:521-526. doi: 10.1016/j.dib.2017.11.040. eCollection 2018 Feb.
Data supporting the angiotensin II activates MEL18 to deSUMOylate HSF2 for hypertension-related heart failure

 

Data Brief. 2017 Nov 20;16:521-526. doi: 10.1016/j.dib.2017.11.040. eCollection 2018 Feb.
Data supporting the angiotensin II activates MEL18 to deSUMOylate HSF2 for hypertension-related heart failure.

 

Elife. 2017 Jun 27;6. pii: e24139. doi: 10.7554/eLife.24139.
Poly(A) tail length regulates PABPC1 expression to tune translation in the heart.

 

PLoS One. 2017 Jun 15;12(6):e0179492. doi: 10.1371/journal.pone.0179492. eCollection 2017.
Protective effect of HDL on NADPH oxidase-derived super oxide anion mediates hypoxia-induced cardiomyocyte apoptosis.

 

J Biol Chem. 2016 Sep 9;291(37):19374-86. doi: 10.1074/jbc.M116.725903. Epub 2016 Jul 22.
Krüppel-like Factor 13 Is a Major Mediator of Glucocorticoid Receptor Signaling in Cardiomyocytes and Protects These Cells from DNA Damage and Death.

 

Development. 2016 Mar 15;143(6):936-49. doi: 10.1242/dev.130971. Epub 2016 Feb 18.
GATA4 regulates Fgf16 to promote heart repair after injury.

 

J Clin Invest. 2015 Nov 2;125(11):4122-34. doi: 10.1172/JCI82423. Epub 2015 Oct 5.
Cardiomyocyte-enriched protein CIP protects against pathophysiological stresses and regulates cardiac homeostasis.

 

Nature. 2015 Sep 24;525(7570):479-85. doi: 10.1038/nature15372. Epub 2015 Sep 16.
Epicardial FSTL1 reconstitution regenerates the adult mammalian heart.

 

Glycobiolog. 2014 Jun;24(6):518-31. doi: 10.1093/glycob/cwu020. Epub 2014 Mar 21.
Lactosylceramide promotes hypertrophy through ROS generation and activation of ERK1/2 in cardiomyocytes.

 

J. Mol Cell Cardiol. 2014 Apr;69:43-51. doi: 10.1016/j.yjmcc.2014.01.017. Epub 2014 Feb 5.
Muscarinic 2 receptors modulate cardiac proteasome function in a protein kinase G-dependentmanner.

 

Circ Res. 2014 Oct 10. pii: CIRCRESAHA.114.304472. [Epub ahead of print]
Alpha-Catenins Control Cardiomyocyte Proliferation by Regulating Yap Activity.

 

Cell Death Differ. 2014 Aug;21(8):1262-74. doi: 10.1038/cdd.2014.46. Epub 2014 May 2.
ANG II promotes IGF-IIR expression and cardiomyocyte apoptosis by inhibiting HSF1 via JNK activation and SIRT1 degradation.

 

Nat Med. 2014 Jun;20(6):616-23. doi: 10.1038/nm.3545. Epub 2014 May 11.
Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies.

 

PLoS One. 2014 Jun 24;9(6):e100715. doi: 10.1371/journal.pone.0100715. eCollection 2014.
Autophagic-lysosomal inhibition compromises ubiquitin-proteasome system performance in a p62 dependent manner in cardiomyocytes.

 

Glycobiology 2014 Jun;24(6):518-31. doi: 10.1093/glycob/cwu020. Epub 2014 Mar 21.
Lactosylceramide promotes hypertrophy through ROS generation and activation of ERK1/2 in cardiomyocytes.

Mishra S1, Chatterjee S.

 

Nat Med. 2014 May 11. doi: 10.1038/nm.3545. [Epub ahead of print]
Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies.

 

Methods Mol Biol. 2014;1071:227-48. doi: 10.1007/978-1-62703-622-1_18.
Integrating fluorescent biosensor data using computational models.

 

J Am Heart Assoc. 2013 Oct 8;2(5):e000461. doi: 10.1161/JAHA.113.000461

Acute inhibition of excessive mitochondrial fission after myocardial infarction prevents long-term cardiac dysfunction.

 

Nat Biotechnol. 2013 Oct;31(10):898-907. doi: 10.1038/nbt.2682. Epub 2013 Sep 8.

Modified mRNA directs the fate of heart progenitor cells and induces vascular regeneration after myocardial infarction.

 

PLoS One. 2013 Oct 3;8(10):e76194. doi: 10.1371/journal.pone.0076194.

Subcellular RNA sequencing reveals broad presence of cytoplasmic intron-sequence retaining transcripts in mouse and rat neurons.

 

Methods Mol Biol 2013;1046:295-306. doi: 10.1007/978-1-62703-538-5_17

Use of the xCELLigence system for real time analysis of changes in cellular motility and adhesion inphysiological

conditions.

 

PLoS One. 2013 Sep 24;8(9):e75580. doi: 10.1371/journal.pone.0075580.

Regulation of PTEN/Akt Pathway Enhances Cardiomyogenesis and Attenuates Adverse Left Ventricular Remodeling following Thymosin β4 Overexpressing Embryonic Stem Cell Transplantation in the Infarcted Heart.

 

J Cell Mol Med. 2013 Jun;17(6):774-81. doi: 10.1111/jcmm.12056.

Formation of functional gap junctions in amniotic fluid-derived stem cells induced by transmembrane co-culture with neonatal rat cardiomyocytes.

 

PLoS One. 2013;8(2):e57052. doi: 10.1371/journal.pone.0057052. Epub 2013 Feb 22. 

Enhanced sensitivity to low dose irradiation of ApoE-/- mice mediated by early pro-inflammatory profile and delayed activation of the TGFβ1 cascade involved in fibrogenesis.

 

Nature. 2012 May 13;485(7400):599-604. doi: 10.1038/nature11139.
Heart repair by reprogramming non-myocytes with cardiac transcription factors.

 

Signal Transduct Res  2012 Jan 24.

α(1A)-Adrenergic receptor differentially regulates STAT3 phosphorylation through PKCϵ and PKCδ in myocytes. 

J Recept Shi T, Papay RS, Perez DM.

 

J Cell Physiol  2012 Jan;227(1):259-68. doi: 10.1002/jcp.22728.

Histone acetylation is essential for ANG-II-induced IGF-IIR gene expression in H9c2 cardiomyoblast cells and pathologically hypertensive rat heart.

 

Nat Genetics  2012 Jan 22;44(3):343-7. doi: 10.1038/ng.1068.

Epigenetic repression of cardiac progenitor gene expression by Ezh2 is required for postnatal cardiac homeostasis.

 

PLoS One 2012;7(10):e47592. doi: 10.1371/journal.pone.0047592. Epub 2012 Oct 15.
a-Catenin localization and sarcomere self-organization on N-cadherin adhesive patterns are myocyte contractility driven.

 

PLoS One 2011;6(12):e29246. Epub 2011 Dec 15.

Sca-1+ cardiac stem cells mediate acute cardioprotection via paracrine factor SDF-1 following myocardial ischemia/reperfusion.

 

 J Biomech. 2011 Dec 23.

Reprogramming cardiomyocyte mechanosensing by crosstalk between integrins and hyaluronic acid receptors.

 

 Am J Cardiovasc Dis. 2011;1(3):214-26. Epub 2011 Jul 28.

Proteasome malfunction activates macroautophagy in the heart.

 

 PLoS ONE. 2011;6(7):e22589. Epub 2011 Jul 21

Acute Vhl gene inactivation induces cardiac HIF-dependent erythropoietin gene expression. 

 

 J. Mol Cell Cardiol.  2011; 51(3): 337-346. Epub 2011 Jun 17

MicroRNA-9 is an activation-induced regulator of PDGFR-beta expression in cardiomyocytes.

 

FASEB J. 2011 Apr 8

Complement dependency of cardiomyocyte release of mediators during sepsis.

 

J Cell Physiol. 2011 May 20. doi: 10.1002/jcp.22847

NADPH oxidase-derived superoxide anion-induced apoptosis is mediated via the JNK-dependent activation of NF-kB in cardiomyocytes exposed to high glucose.

 

J Am Coll Cardiol. 2011 Nov 29;58(23):2415-23. doi: 10.1016/j.jacc.2011.08.033.
Double-edged role of the CXCL12/CXCR4 axis in experimental myocardial infarction.

 

J Clin Invest. 2010 Feb 1;120(2):472-84

Cardiomyocyte PDGFR-beta signaling is an essential component of the mouse cardiac response to load-induced stress.

 

J Clin Invest  2010 Dec 1;120(12):4342-52

T-cadherin is critical for adiponectin-mediated cardioprotection in mice. 

 

Am J Physiol Heart Circ Physiol. 2011 Apr;300(4):H1252-66. Epub 2011 Jan 21.

Cardiac myocyte remodeling mediated by N-cadherin-dependent mechanosensing.

 

J Biomed Sci. 2010 Mar 10;17:16.

Sodium valproate-induced congenital cardiac abnormalities in mice are associated with the inhibition of histone deacetylase.

 

J Biol Chem. 2010 Dec 17;285(51):40312-21. Epub 2010 Oct 14.

Phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2) potentiates cardiac contractility via activation of the ryanodine receptor.

 

J Mol Cell Cardiol. 2010 Sep;49(3):402-11

Correcting diastolic dysfunction by Ca2+ desensitizing troponin in a transgenic mouse model of restrictive cardiomyopathy.

 

Circ Arrhythm Electrophysiol. 2010 Dec 1;3(6):646-56. Epub 2010 Sep 18.

A ZASP missense mutation, S196L, leads to cytoskeletal and electrical abnormalities in a mouse model of cardiomyopathy.

 

Conf Proc IEEE Eng Med Biol Soc. 2010:255-8. doi: 10.1109/IEMBS.2010.5627466.

Textile-templated electrospun anisotropic scaffolds for tissue engineering and regenerative medicine.

 

Hepatology. 2010 Jun;51(6):2097-107.

Hypertrophic cardiomyopathy and dysregulation of cardiac energetics in a mouse model of biliary fibrosis.

 

Dev Biol. 2010 Jan 1;337(1):16-28.

Secondary enhancers synergise with primary enhancers to guarantee fine-tuned muscle gene expression.

 

Gene Ther 2010 Jan;17(1):132-40. Epub 2009 Sep 17.

Dose-dependent restoration of dystrophin expression in cardiac muscle of dystrophic mice by systemically delivered morpholino.

 

J Cell Mol Med. 2009 Sep;13(9B):3655-67.

Akt mediates 17beta-estradiol and/or estrogen receptor-alpha inhibition of LPS-induced tumor necresis factor-alpha expression and myocardial cell apoptosis by suppressing the JNK1/2-NFkappaB pathway.

 

Endocrinology 2009, 150(6): 2723-2731

Activation of Insulin-Like Growth Factor II Receptor Induces Mitochondrial-Dependent Apoptosis through Gq and Downstream Calcineurin Signaling in Myocardial Cells.

 

J Clin Invest.  2009 Jun;119(6):1462-76

Fog2 is critical for cardiac function and maintenance of coronary vasculature in the adult mouse heart.

 

Biochemical and Biophysical Research Communications 2009, 378: 62¨C67

Transcription factor Yin Yang 1 represses fetal troponin I gene expression in neonatal myocardial cells.

 

Am J Physiol Heart Circ Physiol 2009, 296: H1007¨CH1016

Suppression of nitrosative and oxidative stress to reduce cardiac allograft vasculopathy.

 

J. Clin. Invest. 2009; 117(11): 3188-3197

Myocardial hypertrophy in the absence of external stimuli is induced by angiogenesis in mice.

 

J. Cell Mol Med. 2009 Sep; 13(9B):3655-67

Akt Mediates 17¦Â-Estradiol and/or Estrogen Receptor ¦Á Inhibition of LPS-Induced Tumor Necrosis Factor-¦Á Expression and Myocardial Cell Apoptosis by Suppressing the JNK1/2¨CNF¦ÊB Pathway.

 

Molecular Pharmacology. 2009; 76:144-152

Alpha1-Adrenergic Receptor Stimulates Interleukin-6 Expression and Secretion through Both mRNA Stability and Transcriptional Regulation: Involvement of p38 Mitogen-Activated Protein Kinase and Nuclear Factor-B.

 

PLoS ONE. 2009 June 19; 4(6): e5978

Divergent Cardiopulmonary Actions of Heme Oxygenase Enzymatic Products in Chronic Hypoxia.

 

Cardiovasc Res. 2009 Jul 1;83(1):61-71. Epub 2009 Apr 7.

Peroxisome proliferator-activated receptor beta stimulation induces rapid cardiac growth and angiogenesis via direct activation of calcineurin.

 

Cardiovasc Res; 2008 ,80: 181-190

Cardiomyocyte proliferation and protection against post-myocardial infarction heart failure by cyclin D1 and Skp2 ubiquitin ligase.

 

Cardiovascular Toxicology. 2008, 8(2): 71-85

Nuclear Factor E2-Related Factor 2-Dependent Myocardiac Cytoprotection Against Oxidative and Electrophilic Stress.

 

Biophysical Journa. 2008; 95(7): 3479-3487

Substrate Stiffness Affects the Functional Maturation of Neonatal Rat Ventricular Myocytes.

 

J. Cell Biol. 2008; 183(1): 129¨C141

Notch activates cell cycle reentry and progression in quiescent cardiomyocytes.

 

J. Biological Chemistry 2008, 283, 6968-6978.

Identification of a New Co-factor, MOG1, Required for the Full Function of Cardiac Sodium Channel Nav 1.5

 

J. Clin Invest. 2007;117(11):3188–3197.

Myocardial hypertrophy in the absence of external stimuli is induced by angiogenesis in mice.

 

J Mol Cell Cardio. 2007 October; 43(4): 420¨C428

APKC Participates in the Endoplasmic Reticulum Stress-Induced Response in Cultured Cardiac Myocytes and Ischemic Heart.

 

PLoS ONE. 2007 Aug 29; 2(8):e802. 

TrpC3 regulates hypertrophy-associated gene expression without affecting myocyte beating or cell size. 

 

Biochem Biophys Res Commun. 2007 Mar 9; 354(2):372-8. Epub 2007 Jan 17.

Erythropoietin protects cardiac myocytes against anthracycline-induced apoptosis.

 

J Biol Chem. 2007 Jan 19; 282(3):1650-7.

RBCK1, a protein kinase CbetaI (PKCbetaI)-interacting protein, regulates PKCbeta- ependent function.

 

Cardiovascular Res. 2006 Dec 1;72(3):384-93. Epub 2006 Sep 23.

Toll-like receptor stimulation in cardiomyoctes decreases contractility and initiates an NF-kappaB dependent inflammatory response.

 

Cell. 2006 Nov 3; 127(3):591-606.

The C terminus of the L-type voltage-gated calcium channel ca(v)1.2 encodes a transcription factor.

 

Proc Natl Acad Sci U S A. 2006 Aug 22; 103(34):12923-8.

Systems analysis of PKA-mediated phosphorylation gradients in live cardiac myocytes.

 

Cell Biochem Biophys2006; 46(2):113-22.

Chronotropic response of cultured neonatal rat ventricular myocytes to short-term fluid shear. 

 

Nature  2006, 1: 1379-1391.

Micropatterned cell cultures on elastic membranes as an in vitro model of myocardium. 

 

J Pharmacol Exp Ther.2006 Mar; 316(3):999-1005. 

Erythropoietin, modified to not stimulate red blood cell production, retains its cardioprotective properties.

 

Proc Natl Acad Sci U S A. 2005 Oct 11; 102(41):14771-6. 

A positive feedback loop of phosphodiesterase 3 (PDE3) and inducible cAMP early repressor (ICER) leads to cardiomyocyte apoptosis.

 

Cell Biochem Biophys2006; 46(2):113-22.

Chronotropic response of cultured neonatal rat ventricular myocytes to short-term fluid shear. 

 

Nature  2006, 1: 1379-1391.

Micropatterned cell cultures on elastic membranes as an in vitro model of myocardium. 

 

J Pharmacol Exp Ther.2006 Mar; 316(3):999-1005. 

Erythropoietin, modified to not stimulate red blood cell production, retains its cardioprotective properties.

 

Proc Natl Acad Sci U S A. 2005 Oct 11; 102(41):14771-6. 

A positive feedback loop of phosphodiesterase 3 (PDE3) and inducible cAMP early repressor (ICER) leads to cardiomyocyte apoptosis.

 

 

 

 

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All Cellutron products are labeled “For Research Use Only”. Products are not approved for human or veterinary use or for application to humans.

 

 

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